|
|
Assistant professor
|
Accepting graduate students
Research themes
Research affiliations
Research summaryUsing molecular epidemiology techniques, we collaborated in a number of studies aimed at predicting HPV vaccine effectiveness in Canada and internationally. We also have studied the association of specific HPV variants with heightened risk of malignant transformation. We are now getting involved in HPV post-vaccine evaluation to see the effect of the HPV vaccine on the 4 covered types and the remaining HPV types.
We routinely genotype measles, rubella and mumps viruses as part of our duties as a WHO Regional Reference Laboratory for measles and rubella. In particular our lab, in collaboration with the NML’s DNA and Bioinformatics core labs, specializes in whole genome sequencing and extended sequencing for measles for mapping of outbreaks.
We are collaborators of a number of seroepidemiology studies for measles, mumps and varicella and immunity in neonates. These studies aim at evaluating the current immunity status of the Canadian population against these vaccine preventable diseases, at a time of resurgence of measles, mumps and other VPD infections.
Biography
Dr. Alberto Severini obtained his medical degree from the University of Parma, Italy, and did his research training in biochemistry and molecular virology at the University of Alberta. He is currently the Chief of the Viral exanthemata and STD Section at the National Microbiology Laboratory, Public Health Agency of Canada. His laboratory conducts surveillance and reference activities for Human Papilloma and Polyoma Viruses, Herpesviruses, Chlamydia, Measles, Mumps and Rubella. His current research interests include molecular epidemiology of human papillomaviruses, mechanism of HPV carcinogenesis, herpesvirus genomics and measles molecular genetics. Dr. Severini’s laboratory has developed and implemented a number of molecular tests for viral detection and genotyping, especially for HPV, which were used in a number of molecular epidemiology studies. Dr. Severini is on the editorial board of the Journal of Clinical Microbiology and an ad hoc reviewer for numerous scientific journals. He is also a regular grant reviewer for CIHR. He is the author of about 100 publications, with an H-index of 28.Education
ORCID IDhttps://orcid.org/0000-0002-0844-2634
- Masters No
- PhD No
Research themes
- Molecular epidemiology of measles, mumps and rubella
- Molecular epidemiology of human papillomaviruses
- Seroepidemiology of measles mumps, rubella and varicella.
Research affiliations
- Chief, Viral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada
Research summaryUsing molecular epidemiology techniques, we collaborated in a number of studies aimed at predicting HPV vaccine effectiveness in Canada and internationally. We also have studied the association of specific HPV variants with heightened risk of malignant transformation. We are now getting involved in HPV post-vaccine evaluation to see the effect of the HPV vaccine on the 4 covered types and the remaining HPV types.
We routinely genotype measles, rubella and mumps viruses as part of our duties as a WHO Regional Reference Laboratory for measles and rubella. In particular our lab, in collaboration with the NML’s DNA and Bioinformatics core labs, specializes in whole genome sequencing and extended sequencing for measles for mapping of outbreaks.
We are collaborators of a number of seroepidemiology studies for measles, mumps and varicella and immunity in neonates. These studies aim at evaluating the current immunity status of the Canadian population against these vaccine preventable diseases, at a time of resurgence of measles, mumps and other VPD infections.
Biography
Dr. Alberto Severini obtained his medical degree from the University of Parma, Italy, and did his research training in biochemistry and molecular virology at the University of Alberta. He is currently the Chief of the Viral exanthemata and STD Section at the National Microbiology Laboratory, Public Health Agency of Canada. His laboratory conducts surveillance and reference activities for Human Papilloma and Polyoma Viruses, Herpesviruses, Chlamydia, Measles, Mumps and Rubella. His current research interests include molecular epidemiology of human papillomaviruses, mechanism of HPV carcinogenesis, herpesvirus genomics and measles molecular genetics. Dr. Severini’s laboratory has developed and implemented a number of molecular tests for viral detection and genotyping, especially for HPV, which were used in a number of molecular epidemiology studies. Dr. Severini is on the editorial board of the Journal of Clinical Microbiology and an ad hoc reviewer for numerous scientific journals. He is also a regular grant reviewer for CIHR. He is the author of about 100 publications, with an H-index of 28.Education
- Post-doctoral fellowship from Diabetes Canada, University of Alberta (1987-89)
- Post-doctoral fellowship from Alberta Heritage Foundation for Medical Research, University of Alberta (1983-86)
- Specialization in Biochemistry and Clinical Chemistry, University of Parma, Parma, Italy. (1987)
- Medical Degree, University of Parma, Parma Italy (1981)
ORCID IDhttps://orcid.org/0000-0002-0844-2634