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Professor
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Accepting graduate students:
Research interests
Keywords
Gram negative bacteria
Efflux pumps
Resistance-Nodulation-Division
Virulence
Antimicrobial resistance genes
Gene regulation
Research summary
Antibiotic resistance of bacterial pathogens is one of the biggest challenges faced by modern medicine today. With a lack of new antimicrobials in the developmental pipeline, particularly for Gram-negative pathogens, there are concerns that we are headed back to the pre-antibiotic era. Consequently, the World Health Organization (WHO) calls for a pressing need for more research to find effective antimicrobials. Understanding the mechanisms of resistance is key to developing new antimicrobials. Our laboratory focuses on understanding the molecular mechanisms involved in the multidrug resistance of Gram-negative pathogens Acinetobacter baumannii and Pseudomonas aeruginosa. We also study the prevalence of antibiotic resistance in the environment.
Biography
Ayush is a Professor in the Department of Microbiology, University of Manitoba. He is also the Equity, Diversity, and Inclusion lead at the Faculty of Science. He completed is BSc (Microbiology and Biochemistry) and MSc (Microbiology) from Dr. R.M.L. Awadh University, Faizabad, India. His PhD work was carried out in the laboratory of Dr. Elizabeth Worobec, Department of Microbiology, University of Manitoba. Ayush received his post-doctoral training in the laboratory of Dr. Herbert Schweizer, Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft. Collins, CO. He joined the Faculty of Health Sciences at the University of Ontario Institute of Technology (now Ontario Tech University) as an Assistant Professor in 2007. Ayush relocated his laboratory to the University of Manitoba in 2013.Ayush is currently the member of the Executive Committee of Canadian Society of Microbiologists (CSM) as the Past-President. He was the President of the CSM in 2020-2021. He is also the Chair of the CSM Equity, Diversity, Inclusion subcommittee.
Education
Awards
1. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2019.
2. Nominated by the Department of Microbiology for the Dr. and Mrs. Ralph Campbell Outreach Award. 2018.
3. University of Manitoba Merit Award in the Combination of Teaching, Service and Research, Scholarly Work and Other Creative Activities category. 2018.
4. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2018.
5. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2018
6. Mid-Career Researcher Faculty of Science Award for Research Excellence in the Life Sciences. University of Manitoba. 2017.
7. Faculty of Science Award for Outreach. University of Manitoba. 2017.
8. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2017.
9. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2017
10. Outreach Award, University of Manitoba, 2016.
11. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2016.
12. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2016.
13. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2015.
Google ScholarGoogle Scholar: https://scholar.google.ca/citations?user=tBwE4O4AAAAJ&hl=en
- Masters: No
- PhD: No
- Multidrug resistance in Gram-negative bacteria
- Microbiological quality of drinking water from First Nation communities in Manitoba
Research interests
- Determinants of multidrug resistance and virulence in Acinetobacter baumannii
- Molecular mechanisms of assembly of RND efflux pumps of Pseudomonas aeruginosa
- Microbiological quality of drinking water from Manitoba First Nations
Keywords
Gram negative bacteria
Efflux pumps
Resistance-Nodulation-Division
Virulence
Antimicrobial resistance genes
Gene regulation
Research summary
Antibiotic resistance of bacterial pathogens is one of the biggest challenges faced by modern medicine today. With a lack of new antimicrobials in the developmental pipeline, particularly for Gram-negative pathogens, there are concerns that we are headed back to the pre-antibiotic era. Consequently, the World Health Organization (WHO) calls for a pressing need for more research to find effective antimicrobials. Understanding the mechanisms of resistance is key to developing new antimicrobials. Our laboratory focuses on understanding the molecular mechanisms involved in the multidrug resistance of Gram-negative pathogens Acinetobacter baumannii and Pseudomonas aeruginosa. We also study the prevalence of antibiotic resistance in the environment.
Biography
Ayush is a Professor in the Department of Microbiology, University of Manitoba. He is also the Equity, Diversity, and Inclusion lead at the Faculty of Science. He completed is BSc (Microbiology and Biochemistry) and MSc (Microbiology) from Dr. R.M.L. Awadh University, Faizabad, India. His PhD work was carried out in the laboratory of Dr. Elizabeth Worobec, Department of Microbiology, University of Manitoba. Ayush received his post-doctoral training in the laboratory of Dr. Herbert Schweizer, Department of Microbiology, Immunology, and Pathology, Colorado State University, Ft. Collins, CO. He joined the Faculty of Health Sciences at the University of Ontario Institute of Technology (now Ontario Tech University) as an Assistant Professor in 2007. Ayush relocated his laboratory to the University of Manitoba in 2013.Ayush is currently the member of the Executive Committee of Canadian Society of Microbiologists (CSM) as the Past-President. He was the President of the CSM in 2020-2021. He is also the Chair of the CSM Equity, Diversity, Inclusion subcommittee.
Education
- PhD, Microbiology, University of Manitoba (2004)
- Master of Science, Microbiology, Dr. R. M. L. Awadh University, India (1999)
- Bachelor of Science, Microbiology and Biochemistry, Dr. R. M. L. Awadh University, India (1997)
Awards
1. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2019.
2. Nominated by the Department of Microbiology for the Dr. and Mrs. Ralph Campbell Outreach Award. 2018.
3. University of Manitoba Merit Award in the Combination of Teaching, Service and Research, Scholarly Work and Other Creative Activities category. 2018.
4. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2018.
5. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2018
6. Mid-Career Researcher Faculty of Science Award for Research Excellence in the Life Sciences. University of Manitoba. 2017.
7. Faculty of Science Award for Outreach. University of Manitoba. 2017.
8. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2017.
9. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2017
10. Outreach Award, University of Manitoba, 2016.
11. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2016.
12. Outstanding Teacher Award for significant contribution to excellence in teaching. University of Manitoba. 2016.
13. Professor of the Year (3000 level courses). Science Students’ Association, University of Manitoba. 2015.
Google ScholarGoogle Scholar: https://scholar.google.ca/citations?user=tBwE4O4AAAAJ&hl=en